UPTODATE: Acute fatty liver of pregnancy AFLP, characterized by maternal liver dysfunction and microvesicular fatty infiltration of hepatocytes, is rare, with an approximate incidence of 1 in 7000 to 20,000 deliveries. Risk factors include multiple gestation, prior history of AFLP, and male sex of the fetus. AFLP typically presents between the 30th and the 38th gestational week, although it is not always diagnosed prior to delivery. The initial symptoms of AFLP may be nonspecific (eg, nausea, vo