As the nation transforms its healthcare system—with or without the Affordable Care Act (ACA)—it must face the challenge of how to maintain, or even improve, the quality of care. This requires ...

Comparative effectiveness research has been the target of recurrent criticism in some political circles, with opponents claiming it’s the “gateway to rationing” or it encourages “cookbook medicine.” ...

Penny Mohr, MA, senior program officer for improving healthcare systems at the Patient-Centered Outcomes Research Institute, discusses comparative effectiveness research, healthcare disparities, and ...

Comparative effectiveness research increasingly is being recognized as a priority area in cancer research. Although researchers have been conducting comparative effectiveness research for decades, ...

Ellen-Marie Whelan discusses why we need evidence-based health care, how it will improve health, and how we can promote it. The positions of American Progress, and our policy experts, are independent, ...

Charged with ensuring that research produces useful evidence to inform health decisions, the Patient-Centered Outcomes Research Institute (PCORI) requires investigators to engage patients and other ...

The safety profiles of several commonly used advanced therapies for Crohn’s disease appear similar, with no significant differences observed in risks for serious infections and cardiovascular adverse ...

On a daily basis, oncologists and their patients must make choices regarding the approach to treatment. Although treatment selection is often straightforward, decision making in oncology is ...

Comparative effectiveness research in rheumatoid arthritis (RA) that is based on administrative databases rather than electronic health records or registries is a new research frontier The strengths ...

The demand for better evidence to guide healthcare decision making is increasing rapidly for a variety of reasons, including the adverse consequences of care administered without adequate evidence, ...

Comparative effectiveness research is under attack as a new way to limit access to the best health care. Nothing could be further from the truth—in fact, it’s the exact opposite. Comparative ...