Members of a new class of antivirals are being tested in U.S. clinical trials, and one has gained approval in Japan, but how ...

A common hallmark of viral genome replication is a high mutation rate, which can aid in their ability to evade new treatments and acquire resistance to once-effective antiviral medications. Now, a new ...

Researchers identify a shared RNA-protein interaction that could lead to broad-spectrum antiviral treatments for ...

Harvard Medical School researchers have uncovered crucial insights into how an emerging class of antiviral drugs works.

During viral reproduction, the influenza polymerase (top left, in blue) scans along the ribonucleoprotein helix to produce messenger RNA. Credit: Science Like a camera-shy teenager, influenza’s ...

Nipah virus is a zoonotic virus harbored by fruit bats. It can be transmitted to pigs and humans, infect people through contaminated food, and can travel directly from person to person via droplets.

The technology, called the Viral-Engineered RNA-based Activation System (VERAS), hijacks the virus's own replication ...

Researchers uncover how a key human immune protein curbs H5N1 avian flu, but the virus is evolving—could we be on the brink of a new zoonotic threat? Research Letter: Replication Restriction of ...