Gastrointestinal stromal tumours (GISTs) are rare stomach tumours driven by KIT or PDGFRA gene mutations. Unlike typical ...
Confirming a KIT mutation and assessing disease spread are critical initial steps for GIST management. Understanding the mutational profile helps tailor treatment, as some mutations may resist Gleevec ...
Combining surgery with chemotherapy significantly improves survival in GIST patients with liver metastases compared to chemotherapy alone. Median CSS and OS for combined treatment exceed 120 months, ...
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