For decades, Parkinson’s disease has been framed as a straightforward story about dying brain cells and dwindling dopamine. A ...

Explore dopamine's role in movement and how it challenges long-standing theories about motor control and Parkinson's disease treatments.

Submission supported by data from the Phase 3 TEMPO program that demonstrated symptomatic improvement across the Parkinson's disease spectrum Positive results across all three Phase 3 TEMPO trials ...

A new study shows dopamine isn’t the brain’s movement “gas pedal” after all. Instead of setting speed or strength, it quietly ...

A research team led by McGill University has taken a close look at a long-standing idea about Parkinson’s disease and found ...

Researchers uncovered a key cellular regulator, PP2A-B55alpha, that controls both the cleanup of damaged mitochondria and the creation of new ones. In Parkinson’s disease models, reducing this ...

In this Innovation Spotlight, Gene Mack, the chief executive officer of Gain Therapeutics, discusses the company’s Magellan™ platform, which uss machine learning and structural modeling to identify ...

Van Andel Institute and Cure Parkinson's have renewed a funding agreement to support the International Linked Clinical Trials Program, the world's largest drug repurposing clinical trial initiative ...

In the late 1960s, scientists discovered a miracle drug for Parkinson’s disease — a simple, inexpensive dopamine-replacement pill called levodopa. It transformed the lives of millions of people.

Researchers have been chasing the causes of Parkinson’s disease for more than a century, yet its hallmark feature — microscopic protein clumps called Lewy bodies — remains enigmatic: Patients with ...

Marlborough-based pharmaceutical company Sumitomo Pharma America, a U.S. subsidiary of Japanese parent company Sumitomo Pharma, is set to lay off 53 employees, as the company continues to reduce its ...

For years, researchers have watched the tiny power plants inside brain cells falter in Parkinson’s disease and wondered what came first. Did those damaged mitochondria trigger the illness, or did they ...