The sarcoplasmic reticulum (SR) is a specialised organelle in skeletal muscle fibres that plays a pivotal role in regulating calcium dynamics crucial for muscle contraction and relaxation. Acting as ...
A new discovery may explain why so many people abandon cholesterol-lowering statins because of muscle pain and weakness.
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Genetic model reveals a form of calcium release is unnecessary for normal muscle contraction
Instead, CICR acts as a dormant but dangerous silent risk factor, staying quiet under normal conditions yet becoming a major driver of pathology when RyR1 signaling is disrupted. This model resolves a ...
To understand what causes muscle fatigue, it’s worth looking at what exactly muscle fatigue is. If you exercise regularly, you may be familiar with the sensation of a dull ache in your muscles or ...
TORONTO — GLP-1 receptor agonists (RAs) have transformed diabetes and obesity management, offering improvements in glycemic control and weight loss and reductions in cardiometabolic risk. But “an ...
- Muscle cells, also known as myocytes, are specialized cells designed for contraction and force production. Skeletal Muscle Cells: These cells are long, cylindrical, and have a striated (or striped) ...
B.Sc. (Co-op) Pharmacology & Therapeutics, University of British Columbia – 2001 Ph.D., Pharmacology & Therapeutics, University of British Columbia – 2005 My lab's research centres on understanding ...
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