Atropine is a muscarinic antagonist and is indicated for temporary blockage of severe or life threatening muscarinic effects. Atropine Sulfate Injection is now available in an 8mg per 20mL ...

The muscarinic receptor agonist xanomeline has antipsychotic properties and is devoid of dopamine receptor–blocking activity but causes cholinergic adverse events. Trospium is a peripherally ...

Long-acting muscarinic antagonists (LAMAs), as add-on therapy to inhaled corticosteroids, improved peak forced expiratory volume in 1 second (FEV1) and reduced exacerbations in children younger than ...

In a previous article, I made the case that little has changed within the antipsychotic drug landscape over the past 70 years since the only effective medications for the treatment of schizophrenia ...

This is a preview. Log in through your library . Abstract The rate-limiting step in recovery of acetylcholine sensitivity in smooth muscle after exposure to atropine or hyoscine could be the ...

Addressing major unmet needs in mental health with pharmacology rooted in emerging and clinically validated neuropsychiatric biologyLead program ST-905, a potent M1/M4 muscarinic agonist, currently in ...