Ketamine has received a Hollywood makeover. It used to be known as a rave drug (street name special K) and cat anesthetic. However, in recent years, some doctors have prescribed ketamine to treat ...

In a recent study published in Molecular Psychiatry, researchers review the anti-inflammatory effects of ketamine in the peripheral and central nervous systems. To this end, all relevant articles were ...

For individuals facing conditions like depression, anxiety, OCD, or chronic pain, the journey to effective treatment can be long and frustrating. Traditional medications, such as SSRIs, may not always ...

For the nearly 30 percent of major depressive disorder patients who are resistant to treatment, ketamine provides some amount of normalcy, but it requires frequent treatment and can have side effects.

New research addresses a gap in understanding how ketamine's impact on individual neurons leads to pervasive and profound changes in brain network function. A World Health Organization Essential ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, No. 23 (June 10, 2014), pp. 8649-8654 (6 pages) Ketamine is an NMDA receptor (NMDAR) antagonist that elicits ...

Major depressive disorder (MDD) is a leading cause of disability worldwide, with a significant proportion of patients (10-20%) progressing to treatment-resistant depression (TRD). TRD is defined by a ...

A new study sheds light on why the anesthetic and “club drug” ketamine can relieve depression rapidly — in hours, instead of weeks or months. The findings may help provide new targets for developing ...

A spectrogram of brain rhythm frequencies over time predicted by the team's model. After a first, moderate dose of ketamine gamma brain rhythm power (warmer colors) emerges. Then as the dose increases ...