Electrospray ionization mass spectrometry (ESI-MS) has emerged as a pivotal analytical tool, enabling the gentle conversion of analytes in solution into gas-phase ions while minimising fragmentation.

Mass spectrometry (MS) is already perhaps the most popular analytical chemistry tool in drug discovery and development. Its use is ubiquitous in bioanalytical laboratories for drug and metabolite ...

Investigation of leptomeningeal disease in high grade glioma and characterization of molecular alterations. This is an ASCO Meeting Abstract from the 2023 ASCO Annual Meeting I. This abstract does not ...

WEST LAFAYETTE, Ind. — Researchers at Purdue University have used a new technique to rapidly detect and precisely identify bacteria, including dangerous E. coli, without time-consuming treatments ...

Ambient Ionization Techniques Desorption electrospray ionization Desorption electrospray ionization (DESI) involves charged droplets for ionization of analyte molecules in a sample. An electrospray ...

What are the ionization techniques for mass spectrometry? Mass spectrometry (MS) plays a vital role in many aspects of our lives, from diagnosing illness and detecting food contaminants to fighting ...

Researchers have developed a novel technology that allows the distribution of components within a single cell to be accurately detected and visualized. Positioning a t-SPESI (tapping-mode scanning ...

Current drug discovery workflows rely on the synthesis and bioactivity assessment of large compound libraries, both processes which heavily depend on high-throughput (HT) experimentation to be able to ...

Researchers demonstrated the first fully 3D-printed, droplet-emitting electrospray engine. The low-cost device can be fabricated more quickly than traditional thrusters, potentially from on board a ...