By simulating the life cycle of a minimal bacterial cell—from DNA replication to protein translation to metabolism and cell ...

A remarkably small bacterium containing fewer than 500 genes serves as the basis for one of the most detailed digital life ...

By simulating the life cycle of a minimal bacterial cell, from DNA replication to protein translation to metabolism and cell division, scientists have opened a new frontier of computer vision into the ...

Ongoing research aims to confirm the mechanism by which ICP4 fluidizes the nucleus, which could indicate specific targets to counter viral replication.

Working with human breast and lung cells, Johns Hopkins Medicine scientists say they have charted a molecular pathway that can lure cells down a hazardous path of duplicating their genome too many ...

“Our lab is generally interested in discovering and characterizing previously unknown or poorly understood factors that are essential for genome maintenance. This is particularly important in the ...

Sarah J. Aitken is at the Center of Molecular and Cellular Oncology, Yale Cancer Center, New Haven, Connecticut 06511, USA, and in the Department of Pathology, Yale School of Medicine, New Haven. Read ...

Researchers have shown for the first time how Merkel cell polyomavirus (MCV), which causes an aggressive skin cancer called Merkel cell carcinoma, initiates DNA replication in host cells. University ...

A team of researchers at VCU Massey Comprehensive Cancer Center has identified a new pathway through which mutations in the tumor suppressor p53 gene—found very frequently in human tumors—hijack DNA ...

Caulobacter crescentus has emerged as a premier model for studying bacterial cell cycle regulation due to its distinctive asymmetric division, which produces two morphologically and functionally ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified in a new study. In a new paper published in Nature Communications, an ...